Main Dictionary
Half-Life
Time taken for a drug to halve its concentration in blood plasma, It helps determine how much of a drug needs to be taken and how frequently it needs to be taken if a certain average amount is needed constantly. 1
Mechanism of Action (MOA)
The specific biochemical interaction through which a drug substance produces its pharmacological effect.
Standardized Mean Difference (SMD)
SMD values of 0.2 to 0.5 are considered small, 0.5 to 0.8 are considered medium, and greater than 0.8 are considered large.
Used as a summary statistic in meta-analysis when the studies all assess the same outcome but measure it in a variety of ways (for example, all studies measure depression but they use different psychometric scales). In this circumstance it is necessary to standardize the results of the studies to a uniform scale before they can be combined. The standardized mean difference expresses the size of the intervention effect in each study relative to the variability observed in that study.
Blinded Experiment
Experiment in which information about the test is masked to reduce bias. A blind can be imposed on any participant of an experiment, including subjects, researchers, technicians, data analysts, and evaluators.
Proband
In medical genetics and other medical fields, a proband, proposito (male proband), or proposita (female proband) is a particular subject (human or other animal) being studied or reported on [
Implantable Cardioverter Defibrillator (ICD)
An implantable cardioverter defibrillator (ICD) is a medical device that’s surgically placed under the skin on your chest. It consists of a battery and thin wires called leads. The battery is about the size of a stopwatch and the leads go into your heart chambers to regulate your rhythm.
The battery-powered device constantly tracks heart rate and rhythm. Its pulse generator delivers an electric shock when needed to correct arrhythmia. The leads carry the shock to your heart.
ICDs are used to:
- Correct arrhythmia, such as a heart rate or rhythm that’s irregular, too fast (tachycardia) or too slow (bradycardia).
- Prevent sudden cardiac arrest.
- Gather data about your heart’s function to help your healthcare providers make treatment recommendations.
Info
🔥 ICDs = Tachcardia
Cardiac Resynchronization Therapy
Cardiac resynchronization therapy (CRT or biventricular pacing) is a procedure for implanting a permanent biventricular pacemaker. This makes your ventricles (lower chambers in your heart) contract together instead of at different times.
Unlike other pacemakers (including ICDs)2 that have one or two wires or leads, a CRT, or biventricular pacemaker, has three. One lead goes to each of your ventricles. The third goes to your right atrium, one of your heart’s upper chambers. (Your heart has two ventricles and two atria.)
These leads watch for abnormal heart rhythms and send an electrical signal to correct them and make your heart chambers work together.
Cardiac Resynchronization Therapy vs. ICD
Cardiac resynchronization therapy uses a biventricular pacemaker to get your ventricles working together.
An implantable cardioverter-defibrillator (ICD) gets a fast rhythm back to normal. It helps people who have ventricular tachycardia and ventricular fibrillation.
Many people may need a biventricular pacemaker with an ICD to correct all of these issues.3 4
Industry Terms
- B2B: Business to Business
- B2C: Business to Consumer
- B2HCP: Business to Health Care Practitioner
- Benchmark: Goal OR past performance measurement
- CamelCase:
- Campaign: in social media, a campaign refers to either a) a set of ads optimized for a specific objective OR b) all executional elements of a creative campaign
- Channel: a platform chosen to activate a social media campaign on
- CPC: cost per click, ad metric
- CPE: cost per engagement, ad metric
- CPM: Cost per million, this is a advertising metric
- CTR: Click through rate
- DB: Database
- Earned: media coverage, unpaid influencers, social chatter, anything the brand didn’t post and didn’t pay for
- Engagement Rate: Impressions / Engagements - **sometimes reach / engagements when impressions are not available on the platform
- EOD: 5pm in whatever time zone your client is in do your own math
- EOW: 2pm friday in whatever time zone your client is in
- Escalation path: how issues get triaged in social/digital
- Evergreen: not timely content, can be posted at any time
- Flight: Refers to the dates media is running or planned to run
- HVA: High Value Action, typically HVAs happen on a website and are chosen based on their alignment with business objectives
- Impression: # of times a piece of content was served
- KOL: Key opinion leader, dKOL digital KOL
- KPI: Key performance indicator
- Media on demand: a new generation of video on demand, which not only allows users to watch/listen to video and audio content like movies and TV shows, but also provides functions including real-time information, interactive games, attractions guidance, route information, advertising system, shopping & ordering service. Users can select content whenever they want, rather than having to watch it at a specific broadcast time.
- MR: MuckRack
- Owned: channels or content the brand posted from their channels
- Paid: Ad $ were spent
- Parent Comment: First Comment in the thread
- Reach: # of times a piece of content reached a person (sometimes also unique reach)
- Real time content: content that is highly timely, usually around a social media moment (i.e. Fleetwood Mac/Ocean Spray)
- Social Listening: a type of deliverable where we audit social conversations and make insights happen
- SOV: share of voice
- SOW: scope of work
- UVM: Unique monthly views
Medical/Pharma Terms
- AE: adverse event, must be reported to FDA within 24 hours
- AHCP: Aesthetics Health Care Provider (Allergan specific term)
- Cardiac Rhythm Management: pacemakers and similar
- Cath-Lab: refers to cardio surgery room
- Clinician: NOT doctors, other staff
- DDG: Doctor Discussion Guide
- DES: Drug-eluting stent
- Electrophysiology: type of cardiologist that deals with things like AFib and Ablations
- Endovascula: describes a minimally invasive approach commonly done through needle puncture and a sheath.
- Fair Balance: just ask rachel
- HBR: High Bleeding Risk
- HCP: Health Care Provider
- ISI: Important safety info
- MD: Medical Doctor
- MLR: Medical, Legal, Review - **review process with these stakeholders for content approval
- Physicians: Doctors and specialists
- Vascular: traditional vascular surgery is more invasive and involves incisions, which is more surgical in nature.
- Veeva: tool for approvals
Abbott Terms
- Advisor HD Grid: Imaging tool for EP
- Beyond Intervention: Vascular’s thought leadership campaign, also referred to as “BI”
- CardioMEMS: remote monitoring tool for HF
- CentriMag: Device used to bridge the heart in critical care situations
- CN: Creative Network (other agency)
- Confirm RX: Cardiac monitor, connects to an app and your doctor
- CRM: cardiac rhythm management
- CV.A: cardiovascular.abbott.com
- DAPT: dual anti-platelet therapy
- Endofellows: Education program for Fellows (see Greys Anatomy for more detail on Medical School)
- Endomasters: Education program
- Ensite X: Imaging software
- EP: electrophysiology
- EPeeps: Electrophysiologists
- Gallant: pacemaker / crt
- HeartMate: Artificial heart replacement aka (LVAD, left ventricular assist device)
- HF: heart failure
- IC: interventional cardiologists
- IDN: insurance delivery network (example:** Kaiser - **HMOs)
- IR: interventional radiologists
- MitraClip: Structural heart product for leaky valve
- OCT: Imaging software, orange and black colors
- Perclose Proglide: Closure device, used by VAS, EP
- Piccolo: pacemaker for babies
- SH: structural heart
- VS: vascular surgeon (most times)
- XIENCE: a DES (Drug-eluting stent)
Business/General
- 3 portfolio fund: retirement blend you manage yourself, one is basically the whole market (VSTAX, SPY) , one is international (blend of intl), one is mid-small caps (Russel)
- Accredited Investors: individual or company, typically have to have over $1M in assets to qualify and this designation opens up different types of investment options
- Bootstrapping: self-funding a company (i.e. taking no external investment)
- Brokerage Account: Taxable investment account where you buy individual stocks, ETFs and other securities vs. Non-Taxable/IRA/other stuff
- Brokerage: fidelity, vanguard, etrade, Robinhood (don’t use this) - **any company that acts as a broker so you can buy shares of stocks or other securities
- DPO: direct public listing, company lists on NASDAQ directly/sells shares directly to public investor - **first company Spotify, most recently was coinbase
- Fractional shares: means you are buying the right to purchase a share at a percentage you do not actually own this share
- Institutional Investors: big banks/hedge funds, so Goldman Sachs
- IPO: Initial public offering, very popular in tech - **more regulation and fees for listing because it goes through all the the regulatory boards
- M&A: Mergers and acquisitions, refers to when companies merge (join up) with others or are acquired (bought)
- Microinvesting: apps like acorn that take little bits and invest either with AI or allow you to buy specific fractional shares
- Roboadvisors/robobrokerages: AI enabled portfolio management
- Seed funding: initial funding for a company/start up
- Series A/B/C: funding rounds for startups, begins with “seed” and then rounds progressively get larger in terms of actual $
- SPAC: Special-purpose acquisition company; they can change their stock ticker later but the whole point is to acquire companies and get on the market sooner (lots of penny stocks); also a way to circumvent OTCs
- Strike price: price of a stock sale/purchase execution
- Target Index Fund: target date is when you want to retire by, start off very aggressive/high risk and as you get closer to retirement the risk level changes; you go from high amount of stocks to high amount of bonds at the end (WealthFront, Betterment, Ellevest)
- Tax loss harvesting: the write off when you lose $ on too many GME calls, you can write off 2k/year on your losses they also carry over
- VC: Venture Capital